Correction of eye-motion artifacts in AO-OCT data sets

Eye movements present during acquisition of a retinal image with optical coherence tomography (OCT) introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in highresolution data sets acquired with adaptive optics (AO)-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AOOCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AOSLO) images. We extract transverse eye motion data from the AO-SLO images, assign a motion adjustment vector to each AO-OCT A-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.